The critical parameters of pyridine are pressure 6.70 MPa, temperature 620 K and volume 229 cm3·mol−1. 766-11-0, formula is C5H3BrFN, Name is 5-Bromo-2-fluoropyridine. In the temperature range 340–426 °C its vapor pressure p can be described with the Antoine equation.. Synthetic Route of 766-11-0.
Dang, Hang T.;Nguyen, Viet D.;Haug, Graham C.;Vuong, Ngan T. H.;Arman, Hadi D.;Larionov, Oleg V. research published 《 Z-Selective Dienylation Enables Stereodivergent Construction of Dienes and Unravels a Ligand-Driven Mechanistic Dichotomy》, the research content is summarized as follows. A highly Z-selective dienylation can now be achieved by a simple adjustment of a ligand, enabling stereodivergent synthesis of E- and Z-dienes RCH=CHCH=CH2 (R = 4-cyanophenyl, 5-chloropyridin-3-yl, 2-methylpyrimidin-5-yl, etc.) from one reagent and in one step. A detailed mechanistic investigation of the E- and Z-selective dienylation provided insight into the divergent behavior of the two catalytic systems and revealed that differences in relative stabilities of catalytically active palladium phosphine complexes e.g., bis(1,2-bis(diphenylphosphino)benzene)palladium(0) have a major impact on the stereochem. outcomes of the dienylation.
766-11-0, 5-Bromo-2-fluoropyridine is a useful research compound. Its molecular formula is C5H3BrFN and its molecular weight is 175.99 g/mol. The purity is usually 95%.
5-Bromo-2-fluoropyridine is a boronic acid that has been shown to react with iodides and form 5-bromo-2-fluoroiodobenzene. The reaction of 5-bromo-2-fluoropyridine with benzene gives the same product as the reaction with 1,3,5-trioxane. The UV absorption of 5-bromo-2-fluoropyridine is found at 230 nm and 260 nm. It also has an absorption band in the infrared region at 1625 cm−1. Vibrational progressions have been observed for this molecule, which are due to dipole moments and electron density distributions in the molecule.
5-bromo-2-fluoropyridine is used in the synthesis of heteroaromatic and aniline derivatives of piperidines as potent ligands used for vesicular acetylcholine transport. , Synthetic Route of 766-11-0