《Proximity effects in pyridines. Proton chemical shifts in substituted methyl pyridinecarboxylates》 was published in Organic Magnetic Resonance in 1975. These research results belong to Deady, L. W.; Harrison, P. M.; Topsom, R. D.. HPLC of Formula: 29681-39-8 The article mentions the following:
The chem. shifts in 6 series of substituted Me pyridinecarboxylates were measured and interpreted in terms of proximity effects. The shifts for ring H ortho and para to the substituent were explained by additive ester, nitrogen, and substituent effects. The results for meta H indicated substituent-nitrogen interactions, especially when both substituent and H were adjacent N. Similar results were obtained for the ester H. The experimental part of the paper was very detailed, including the reaction process of Methyl 5-methoxypicolinate(cas: 29681-39-8HPLC of Formula: 29681-39-8)
Methyl 5-methoxypicolinate(cas: 29681-39-8) belongs to pyridine. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Additionally, pyridine-based natural products continue to be discovered and studied for their properties and to understand their biosynthesis.HPLC of Formula: 29681-39-8