A versatile synthesis of carboxypyridine betaines and their 1H and 13C NMR spectra was written by Dega-Szafran, Zofia;Kowalczyk, Iwona;Szafran, Miroslaw. And the article was included in Bulletin of the Polish Academy of Sciences, Chemistry in 1996.Recommanded Product: 27876-24-0 This article mentions the following:
Pyridine betaine and 15 substituted betaines, I (R = 2-, 3-, 4-Me, 4-Et, 4-CMe3, 3,4-Me2, etc.), were prepared by alkylation of the corresponding R-substituted pyridines with Et chloroacetate. The ester group was removed by acid hydrolysis and the obtained hydrochlorides were subsequently reacted with propylene oxide in order to obtain pure, free R-pyridine betaines I. The 1H and 13C NMR spectra of free betaines and their hydrochlorides were analyzed with respect to interaction of the ring substituents with the N+CH2COO group. In the experiment, the researchers used many compounds, for example, 4-Hexylpyridine (cas: 27876-24-0Recommanded Product: 27876-24-0).
4-Hexylpyridine (cas: 27876-24-0) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ璺痬ol閳? in pyridine vs. 150 kJ璺痬ol閳? in benzene). Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Recommanded Product: 27876-24-0