In 2016,Deutsch, Amrei; Jessen, Christoph; Deutsch, Carl; Karaghiosoff, Konstantin; Hoffmann-Roeder, Anja published 《One-Pot Synthesis of Substituted Trifluoromethylated 2,3-Dihydro-1H-imidazoles》.Organic Letters published the findings.Recommanded Product: 5-Bromo-2-chloropyridine The information in the text is summarized as follows:
An operationally simple one-pot reaction for the preparation of a novel class of racemic trifluoromethylated 2,3-dihydro-1H-imidazoles derived from electron-poor N,O-acetals and aryl Grignard reagents is described. In addition, access to highly functionalized 2-trifluoromethyl-2,3-dihydro-1H-imidazoles was accomplished by reaction of N-aryl hemiaminal ethers and N-aryl trifluoroethylamines in the presence of an excess of n-butyllithium. In the part of experimental materials, we found many familiar compounds, such as 5-Bromo-2-chloropyridine(cas: 53939-30-3Recommanded Product: 5-Bromo-2-chloropyridine)
5-Bromo-2-chloropyridine(cas: 53939-30-3) belongs to pyridine. Pyridines form stable salts with strong acids. Pyridine itself is often used to neutralize acid formed in a reaction and as a basic solvent. Recommanded Product: 5-Bromo-2-chloropyridine