Devi, Lalita; Kumar, Prashant; Kant, Ruchir; Rastogi, Namrata published the artcile< Exploiting the umpolung reactivity of diazo groups: direct access to triazolyl-azaarenes from azaarenes>, Name: 3-(Methoxycarbonyl)pyridine, the main research area is triazolyl isoquinoline pyridine phenanthridine preparation; azaarene diazo iodonium triflate tandem electrophilic substitution dipolar cycloaddition.
The present work documents electrophilic substitution of azaarenes, mainly isoquinolines, with hypervalent iodine diazo reagents (HIDR) followed by formal [3+2]-dipolar cycloaddition in a tandem fashion. Other azaarenes viz. pyridines and phenanthridines too could be successfully used in the reaction. The methodol. capitalizes on the umpolung nature of α-aryliodonio diazo compounds for installing a nucleophile, i.e. azaarene, at their α-position. Subsequent ylide formation and intramol. 1,5-cyclization furnished 4,3-fused 1,2,4-triazolyl-azaarenes in good yields. The reaction is notable for its mild conditions, operational simplicity and fairly general scope.
Chemical Communications (Cambridge, United Kingdom) published new progress about [3+2] Cycloaddition reaction. 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Name: 3-(Methoxycarbonyl)pyridine.