《Chromogenic hydrazide Schiff base reagent: Spectrophotometric determination of CN- ion》 was published in Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy in 2020. These research results belong to Dey, Sunanda; Sen, Chandana; Sinha, Chittaranjan. Name: Picolinic acid The article mentions the following:
A Schiff base reagent, Picolinohydrazide-naphthol (HL), was used for trace level detection of toxic CN- selectively in presence of eighteen other anions (SCN-, OCN-, S2O2-3, HPO2-4, H2PO-4, I-, ClO-4, HSO-4, SO2-4, AsO3-4, NO-2, AsO-2, Cl-, F-, HF-2, NO-3, Br-, N-3) by visual color change, colorless to yellow, in DMSO/H2O (9:1, volume/volume) at pH, 7.2 (HEPES buffer) medium. The sensitivity of the probe shows that the limit of detection (LOD) is 7.08μM. The probable mechanism for the sensing behavior involves the deprotonation of naphthol-OH by CN- that was authenticated by 1H NMR titration and Mass spectra. The composition (1:1 mol ratio) is supported by Job’s plot and binding constant (Ka, 1.5 × 104 M-1) is reported by Benesi-Hildebrand plot. Also, a simple paper strip device is fabricated for the determination of CN- ion in water. DFT computation is carried out to explain the electronic spectral feature of the sensor.Picolinic acid(cas: 98-98-6Name: Picolinic acid) was used in this study.
Picolinic acid(cas: 98-98-6) is used in the preparation of 2-Aminodihydro[1,3]thiazines as BACE 2 inhibitors and their preparation and use in the treatment of diabetes.Name: Picolinic acid