So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Wang, Yifeng; Ma, Chenggong; Zheng, Xuwei; Ju, Minzi; Fu, Yongqian; Zhang, Xing; Shen, Baoxing researched the compound: 2,4-Dimethyl-1H-pyrrole( cas:625-82-1 ).Reference of 2,4-Dimethyl-1H-pyrrole.They published the article 《A red emission multiple detection site probe for detecting carboxylesterase 1 based on BODIPY fluorophore》 about this compound( cas:625-82-1 ) in Journal of Photochemistry and Photobiology, A: Chemistry. Keywords: BODIPY fluorophore carboxylesterase red emission multiple detection. We’ll tell you more about this compound (cas:625-82-1).
In this work, a BODIPY-based multi-site red emission fluorescent probe MRS-BOD for the detection of carboxylesterase 1 (CES1) was designed and synthesized. MRS-BOD showed good biocompatibility and could be used to monitor the activity of CES1 in living cells. MRS-BOD emission is located in the red emission region, which has the advantages of less background interference and less damage to biol. samples. MRS-BOD has multiple CES1 recognition sites, and the ultra-sensitive quantification of CES1 has been successfully achieved. The low detection limit of MRS-BOD was calculated as 2.5 ng/mL, and the fluorescence quantum yield was calculated as 0.49. This study can promote the development of CES1 fluorescent probes and help the identification of related diseases.
Although many compounds look similar to this compound(625-82-1)Reference of 2,4-Dimethyl-1H-pyrrole, numerous studies have shown that this compound(SMILES:CC1=CNC(C)=C1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.