Tanaka, N; Usuki, T in [Tanaka, Nao; Usuki, Toyonobu] Sophia Univ, Dept Mat & Life Sci, Fac Sci & Technol, Chiyoda Ku, 7-1 Kioicho, Tokyo 1028554, Japan published Can Heteroarenes/Arenes Be Hydrogenated Over Catalytic Pd/C Under Ambient Conditions? in 2020.0, Cited 79.0. Recommanded Product: 91-02-1. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1.
Hydrogenation of over a dozen aromatic compounds, including both heteroarenes and arenes, over palladium on carbon (Pd/C, 1-100 mol%) with H-2-balloon pressure at room temperature is reported. Analyses using pyridine as a model substrate revealed that acetic acid was the best solvent, as using only 1 mol% Pd/C provided piperidine quantitatively. Substrate scope analysis and density functional theory calculations indicated that reaction rates are highly dependent on frontier molecular orbital characteristics and the steric bulkiness of substituents. Moreover, the established method was used for the concise synthesis of the anti-Alzheimer drug donepezil (Aricept (R)).
Recommanded Product: 91-02-1. Welcome to talk about 91-02-1, If you have any questions, you can contact Tanaka, N; Usuki, T or send Email.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem