Electric Literature of C33H24IrN3In 2021 ,《Photocatalytic Radical Ortho-Dearomative Cyclization: Access to Spiro[4.5]deca-1,7,9-trien-6-ones》 was published in Journal of Organic Chemistry. The article was written by Dong, Wuheng; Yuan, Yao; Liang, Caiyun; Wu, Feng; Zhang, Siyuan; Xie, Xiaomin; Zhang, Zhaoguo. The article contains the following contents:
A highly efficient ortho-dearomative cyclization reaction between alkynes and 2-bromo-2-(2-methoxybenzyl)malonates via visible light-induced photoredox catalysis has been reported. In the presence of 1 mol% fac-Ir(ppy)3, a variety of spiro[4.5]deca-1,7,9-trien-6-ones, e.g., I, was obtained in moderate to excellent yields under mild conditions. Under the optimized reaction conditions, a sample reaction of 3 mmol scale proceeded smoothly to give the desired products in 84% yield with a low catalyst loading of 0.1 mol%. In the experiment, the researchers used fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6Electric Literature of C33H24IrN3)
fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6) belongs to pyridine. Pyridines, quinolines, and isoquinolines have found a function in almost all aspects of organic chemistry. Pyridine has found use as a solvent, base, ligand, functional group, and molecular scaffold. As structural elements, these moieties are potent electron-deficient groups, metal-directing functionalities, fluorophores, and medicinally important pharmacophores. Electric Literature of C33H24IrN3