Dubash, Pesi J.; Rege, Dinanath V. published an article in 1968, the title of the article was Chlorophyll formation in Euglena gracilis var bacillaris. Interference by vitamin analogs.HPLC of Formula: 636-73-7 And the article contains the following content:
The relations between vitamins and chlorophyll synthesis in non-proliferating E. gracilis var bacillaris cells were studied. Although vitamin B12 deficiency increased cell size and cell mass in light-grown Euglena, it did not significantly affect chlorophyll synthesis. Furthermore, inhibition of chlorophyll synthesis by 2,6-diaminopurine, an antimetabolite of vitamin B12, was not abolished by vitamin B12. Other vitamin B12 antimetabolites, such as 6-mercaptopurine, sulfanilamide, and benzimidazole, did not inhibit pigment synthesis. Inhibition of chlorophyll synthesis by isoniazid (2000 μg./ml.) was not relieved by niacin (200 μg./ml.). In fact, niacin itself inhibited both growth and pigment synthesis. However, inhibition by niacin was prevented by pyridine-3-sulfonate (200 g./ml.). Niacin and its analogs, isoniazid and niacinamide, were also more inhibitory to growth in the dark than in the light. Inhibition of growth by niacin in the light was relieved by 1% glucose or pyruvate and by a large concentration (5000 μμg./ml.) of vitamin B12. Aminopterin, deoxypryridoxine, and 2-chloro-p-aminobenzoic acid did not affect chlorophyll synthesis in nonproliferating Euglena. However, 2-chloro-p-aminobenzoic acid (25 μg./ml.) inhibited growth 63.8% in the dark and 54.0% in the light. Thiamine deficiency inhibited growth, and such suboptimally grown Euglena also synthesized less chlorophyll during subsequent illumination under non-proliferation conditions. The neg. growth response of light-grown Euglena to niacin up to concentrations of 70 μg./ml. suggested that this organism could be used for the bioassay of niacin. The 50% growth inhibition level for niacin in the light was 46 μg./ml. 23 references. The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).HPLC of Formula: 636-73-7
The Article related to chlorophyll formation euglena, vitamin interference chlorophyll, euglena formation chlorophyll, chlorophylls role: biol (biological study), euglena, vitamins and other aspects.HPLC of Formula: 636-73-7