Cycloparaffins fused with heterocyclic rings. Part XXXII. A convenient synthesis of 2- or 3-alkyl- and 2,3-dialkylpyridines and cycloalkeno[b]pyridines was written by Epsztajn, Jan;Bieniek, Adam;Brzezinski, Jacek Z.. And the article was included in Polish Journal of Chemistry in 1980.Reference of 644-98-4 This article mentions the following:
Pyridines I [R = CHMe2, Ph, H, Et, Pr; R1 = H, Et, CH2Ph, Me; RR1 = (CH2)3-6] were prepared by treating R1CH:CRR2 (R2 = NMe2, morpholino) with CH2:CHCHO to give 33-70% RCOCHR1CH2CH2CHO, which were treated with NH2OH.HCl in EtOH to give 15-74% I. In the experiment, the researchers used many compounds, for example, 2-Isopropylpyridine (cas: 644-98-4Reference of 644-98-4).
2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Reference of 644-98-4