Application In Synthesis of 3-Cyanopyridine《Synthesis, X-ray structure, Hirshfeld, and antimicrobial studies of new Ag(I) complexes based on pyridine-type ligands》 was published in 2022. The authors were El-Naggar, Mostafa A.;Abu-Youssef, Morsy A. M.;Soliman, Saied M.;Haukka, Matti;Al-Majid, Abdullah Mohammed;Barakat, Assem;Badr, Ahmed M. A., and the article was included in《Journal of Molecular Structure》. The author mentioned the following in the article:
The two silver(I) complexes [Ag(3CNPy)2(CF3COO)]n (1) and [Ag(4BzPy)2]2(CF3COO)2 (2) where 3CNPy and 4BzPy are 3-cyanopyridine and 4-benzoylpyridine, resp., were synthesized and characterized using elemental anal., FTIR spectra and single crystal x-ray diffraction. Complex 1 is a 1D coordination polymer through the bridging and the highly sym. CF3COO group while 2 is a dinuclear complex through strong argentophilic interaction connecting the two [Ag(4BzPy)2] cationic units. In both complexes, the pyridine ligands are acting as monodentate N-donor. Hirshfeld surface anal. revealed the importance of the polar N···H (29.9%) and H···F (10.3%) hydrogen bonds in the mol. packing of 1. For 2, the nonpolar C···H (26.2%) and the polar O···H (15.6%) interactions dominate the crystal packing. Furthermore, both complexes showed π-π stacking interactions. Antimicrobial screening revealed that 3CNPy has no activity against all tested pathogens, while 1 has good antibacterial activity. Both Ag(I) complexes and 4BzPy showed remarkable antifungal activities against A. fumigatus and C. albicans compared to Ketoconazole as control. To complete the study, the researchers used 3-Cyanopyridine (cas: 100-54-9) .
3-Cyanopyridine(cas: 100-54-9) is an antimicrobial agent that can be used in the treatment of infectious diseases.Application In Synthesis of 3-Cyanopyridine It has been shown to be effective against a variety of bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and Streptococcus pneumoniae.