Electric Literature of 1594-58-7, Adding some certain compound to certain chemical reactions, such as: 1594-58-7, name is N-Hydroxynicotinimidamide,molecular formula is C6H7N3O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1594-58-7.
General procedure: Parent amidoxime (2mmol) was dissolved in the indicated solvent (0.15M) and cooled to 0C under an argon atmosphere. Triethylamine (0.28mL, 2mmol) was added, followed by the required sulfonyl chloride (2mmol) and the mixture was stirred for the indicated period allowing the temperature to slowly rise to 25C. Then, water (70mL) was added and the mixture was extracted with dichloromethane (2×70mL). The combined organic extracts were dried (Na2SO4) and concentrated under vacuum (rotary evaporator) to give a residue which was either recrystallized or purified using column chromatography.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 1594-58-7, N-Hydroxynicotinimidamide, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Doulou, Ismini; Kontogiorgis, Christos; Koumbis, Alexandros E.; Evgenidou, Eleni; Hadjipavlou-Litina, Dimitra; Fylaktakidou, Konstantina C.; European Journal of Medicinal Chemistry; vol. 80; (2014); p. 145 – 153;,
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