Related Products of 609-71-2, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 609-71-2, name is 2-Oxo-1,2-dihydropyridine-3-carboxylic acid, molecular formula is C6H5NO3, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
(d) 5- Bromo-2-hydroxy-nicotinic acid To a suspension of 5.0 g (35.9 mmol) of 2-hydroxy-nicotinic acid in 30 ml acetic acid was added dropwise 7.5 g (46.7 mmol) bromine. The mixture was maintained at 70-80 C. overnight. The mixture was cooled and the acetic acid was removed under reduced pressure. Water (100 ml) was added and the product was filtered and washed with water (3*100 ml). The solid was dried in a vacuum oven at 65 C. for 48 hours to provide 6.1 g (78% yield) of the title compound. MS: m/z (APCI, AP+) 219.0 [M¡¤]+. CHN Analysis: Calcd: C, 33.06; H, 1.85; N, 6.42. Found: C, 32.91; H, 1.78; N, 6.23.
According to the analysis of related databases, 609-71-2, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Barvian, Nicole Chantel; Connor, David Thomas; O’Brien, Patrick Michael; Ortwine, Daniel Fred; Patt, William Chester; Shuler, Kevon Ray; Wilson, Michael William; US2002/161000; (2002); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem