Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 6980-08-1, name is 4-Chloro-3-nitropyridin-2-amine. This compound has unique chemical properties. The synthetic route is as follows. Application In Synthesis of 4-Chloro-3-nitropyridin-2-amine
2-Amino-3-nitro-4-chloropyridine (967 mg, 5.59 mmol) was dissolved in isopropanol (20 mL) and DIPEA (1.85 mL, 11.18 mmol) was added followed by N-methylpiperazine (0.744) mL, 6.71 mmol). The mixture was reacted at 90 C. for 12 h. A large amount of gold solid was isolated by cooling and was filtered, washed with isopropyl alcohol and ether in that order, and dried in vacuo to give the title compound (1.21 g, yield 92%) as a golden yellow solid.
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Reference:
Patent; Chinese Academy Of Sciences Shanghai Pharmaceutical Institute; Long Yaqiu; Cao Bin; (103 pag.)CN103570683; (2018); B;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem