Related Products of 1003-68-5, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1003-68-5, name is 5-Methylpyridin-2(1H)-one. This compound has unique chemical properties. The synthetic route is as follows.
Sequentially adding to the reaction bottle 5-methyl -2 (1H)-pyridone 109 g, anhydrous potassium carbonate 165 g, cuprous bromide 0.72 g, bromophenylacetic 188.4 g, 1,10-phenan throline 0.9 g and N, N-dimethyl formamide 500 ml, the mixture is heated to 90 C about 2 hours, cooling to the end 25 C, by adding 2000 ml of water mixing, filtering, in the filter cake into the reaction bottle, by adding 5% acetic acid aqueous solution 1500 ml, the temperature is increased to 90 C, filtration, filtrate with 20% sodium hydroxide solution to adjust the pH= 13, and then cooled to the 5 C the following filtering, decompression drying to obtain the pirfenidone 132.5 g, spare.
According to the analysis of related databases, 1003-68-5, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Chongqing Kangle Pharmaceutical Co., Ltd; Tang, Ming; Chen, Wenhui; Chen, Lin; Ma, Xiaoping; Zheng, Xue; Yang, Jibin; Cai, Zhongwen; Wang, Yachuan; (6 pag.)CN105315198; (2016); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem