Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 625-82-1, is researched, SMILESS is CC1=CNC(C)=C1, Molecular C6H9NJournal, Article, Research Support, Non-U.S. Gov’t, Organic & Biomolecular Chemistry called Red fluorescent pyrazoline-BODIPY nanoparticles for ultrafast and long-term bioimaging, Author is Zhang, Yuandong; Zheng, Xiaohua; Zhang, Liping; Yang, Zhiyu; Chen, Li; Wang, Lei; Liu, Shi; Xie, Zhigang, the main research direction is red fluorescent pyrazoline BODIPY nanoparticle bioimaging.Safety of 2,4-Dimethyl-1H-pyrrole.
Fluorescence bioimaging is very significant in studying biol. processes. Fluorescent nanoparticles (NPs) manufactured from aggregation-induced emission (AIE) materials, as promising candidates, have attracted more attention. However, it is still a challenge to explore suitable AIE NPs for bioimaging. Herein, the authors synthesized pyrazoline-BODIPY (PZL-BDP) with a donor and acceptor (D-A) structure by a condensation reaction, cultured its single crystal, and studied its twisted intramol. charge transfer (TICT) and AIE effects. PZL-BDP could self-assemble to form red fluorescent nanoparticles (PZL-BDP NPs) which showed a good fluorescence quantum yield of 15.8% in water. PZL-BDP NPs with excellent stability and biocompatibility exhibited a large Stokes shift (Δλ = 111 nm) which resulted in the reduction of external interference and enhancement of the fluorescence contrast. Furthermore, these nanoparticles could be readily internalized by HeLa cells and they stain the cells in just five seconds, indicating an ultrafast bioimaging protocol. Moreover, long-term tracking fluorescence signals in vivo for ∼12 days were obtained. The bright red fluorescence, ultrafast cell staining ability, and long-term in vivo tracking competence outline the great potential of rational design nanomaterials with AIE characteristics for monitoring biol. processes.
In some applications, this compound(625-82-1)Safety of 2,4-Dimethyl-1H-pyrrole is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.