In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 769-54-0, name is 3-Fluoro-4-nitropyridine 1-oxide, the common compound, a new synthetic route is introduced below. Application In Synthesis of 3-Fluoro-4-nitropyridine 1-oxide
To a mixture suspension of 3-fluoro-4-nitropyridine 1-oxide (9.75 g, 61.7 mmol) and methanol (145 mL) was added 28% sodium methoxide methanol solution (11.9 g, 61.7 mmol) with cooling with ice. This mixture was heated to room temperature and stirred for 1 hour at the temperature. The methanol was distilled off under reduced pressure. Water (50 mL) was added to the residue, followed by extracting with chloroform. The organic layer was washed with brine, and anhydrous sodium sulfate was added to dry the layer. After anhydrous sodium sulfate was removed by filtration, the solvent was distilled off under reduced pressure to obtain 3-methoxy-4-nitropyridine 1-oxide (9.54 g; yield, 91%).
The synthetic route of 769-54-0 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; ISHIHARA SANGYO KAISHA, LTD.; KIRIYAMA, Kazuhisa; MATSUMOTO, Masahiro; YOSHIDA, Kotaro; BOLDBAATAR, DamdinSuren; JUKUROGI, Tatsuya; UMEMOTO, Nao; KANI, Tatsuya; MATSUDA, Yoko; TANAKA, Kumiko; KANUMA, Michiko; SHIMADA, Tatsuya; WO2014/98259; (2014); A1;,
Pyridine – Wikipedia,
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