Application of 896139-85-8, Adding some certain compound to certain chemical reactions, such as: 896139-85-8, name is Imidazo[1,2-a]pyridin-7-ol,molecular formula is C7H6N2O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 896139-85-8.
A solution of imidazo [1,2-a] pyridine-7-ol (218 mg, 1.63 mmol)N-Boc-4-hydroxypiperidine (654 mg, 3.25 mmol) and Ph3P (1.71 g, 6.52 mmol) were dissolved in THF (30 mL)Then DBAD (748 mg, 3.25 mmol) dissolved in THF (10 mL) was added dropwise to the reaction solution at 0 C,After the room temperature reaction is complete,The product was quenched by the addition of water to give the product 7 (250 mg, 48%) by vacuum spin column chromatography.
According to the analysis of related databases, 896139-85-8, the application of this compound in the production field has become more and more popular.
Reference:
Patent; East China Normal University; Hu Wenhao; Xi Jianbei; Lei Ruirui; Zhu Mengli; Ma Mingliang; Xiao Guolan; Zhang Xiongwen; Fang Yanfen; Li Hongyu; (28 pag.)CN106496222; (2017); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem