Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 98027-84-0, name is 2,6-Dichloro-4-iodopyridine. This compound has unique chemical properties. The synthetic route is as follows. Recommanded Product: 2,6-Dichloro-4-iodopyridine
Example 1A 6-chloro-N-cyclohexyl-4-iodopyridin-2-amine A mixture of 2,6-dichloro-4-iodopyridine (5 g, 18.3 mmol) and cyclohexylamine (18.1 g, 183 mmol) was heated in a Biotage Initiator microwave at 150 C. for 30 min. Ethyl acetate (150 mL) was added and the mixture washed with water (100 mL) and brine (50 mL). The organics were concentrated and the residual oil purified by flash chromatography on silica gel eluding with 10% ethyl acetate in hexanes to provide the title compound. Yield: 4.7 g (76%). MS (DCI/NH3) m/z 337 (M+H)+.
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Reference:
Patent; ABBOTT LABORATORIES; US2011/15172; (2011); A1;,
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