In an article, author is Elmagbari, Fatin M., once mentioned the application of 6298-19-7, Name is 2-Chloropyridin-3-amine, molecular formula is C5H5ClN2, molecular weight is 128.5596, MDL number is MFCD00006238, category is pyridine-derivatives. Now introduce a scientific discovery about this category, Recommanded Product: 6298-19-7.
Stability, solution structure and X-ray crystallography of a copper (II) diamide complex
It has been shown that the inflammation associated with rheumatoid arthritis can be reduced using copper complexes. In order to improve the bioavailability of copper and hence efficacy, 3-(2-aminoacetamido)-N-(pyridin-2-ylmethyl)propanamide, H-2(5 6 5)NH2, was designed as a potential chelator of copper. Solution equilibrium measurements show that the [Cu(LH-2)] species predominates at physiological pH and blood plasma speciation calculations predict that this ligand is able to mobilise Cu(II) in vivo. A structural study of the Cu(II)/H-2(5 6 5)NH2 system was conducted in the solid and solution state using Uv-Vis, CD, H-1 NMR and EPR spectroscopy and single crystal X-ray crystallography. The result indicate that the structure of [Cu(H-2(5 6 5)NH2)H-2] in the solid and solution state are similar and confirm that, the metal binds to the pyridine nitrogen, the two amide nitrogens and the terminal amino group in a distorted square planar geometry.
Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 6298-19-7, Recommanded Product: 6298-19-7.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem