Adding a certain compound to certain chemical reactions, such as: 55676-21-6, 1-(2-Chloropyridin-3-yl)ethanone, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 55676-21-6, blongs to pyridine-derivatives compound. Product Details of 55676-21-6
KOH (0.5 N MeOH, 6.0 mL, 3.0 mmol) was added to a solution of the compound 6 (467 mg, 3.0 mmol) prepared in Example 1 and 2-methoxybenzaldehyde (408 mg, 3.0 mmol) in THF The reaction was stopped by adding 0.5 N HCl (6 mL) to the mixed light yellow solution at 0 ° C and mixing at 0 ° C to room temperature for 3 hours. After evaporation of the solvent from this solution, the mixture was taken up in saturated NaHCO3 solution (30 mL) and extracted three times with dichloromethane (20 mL). The concentrated residue was purified by silica gel column chromatography using 30percent EtOAc / n-hexane as the extraction solvent to give compound 7l (673 mg, 82percent).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,55676-21-6, its application will become more common.
Reference:
Patent; Duksung Women’s University Industry-Academic Cooperation Foundation; Jae, In Lee; (15 pag.)KR101766414; (2017); B1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem