Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 103-74-2, name is 2-(2-Hydroxyethyl)pyridine. A new synthetic method of this compound is introduced below., Application In Synthesis of 2-(2-Hydroxyethyl)pyridine
Aqueous HBr (2.5 L) was charged into a clean and dry round bottom flask followed by compound (9) (250 g, 2.03 mol) and heated to 120 C with azeotropical removal of water (-24 h). The residual water was removed by co-distillation with toluene (2 x 2 L), thesolid was stined in MTBE: IPA (1:1) for 1 h and filtered, washed with MTBE (200 ml) and dried in vacuum, yielding 360 g (66%) of light pink solid (compound (10)).
If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 103-74-2, 2-(2-Hydroxyethyl)pyridine.
Reference:
Patent; MAPI PHARMA LTD.; MAROM, Ehud; RUBNOV, Shai; (44 pag.)WO2016/132343; (2016); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem