Extracurricular laboratory: Synthetic route of 2-Amino-3-iodopyridine

The synthetic route of 104830-06-0 has been constantly updated, and we look forward to future research findings.

Adding a certain compound to certain chemical reactions, such as: 104830-06-0, 2-Amino-3-iodopyridine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Recommanded Product: 2-Amino-3-iodopyridine, blongs to pyridine-derivatives compound. Recommanded Product: 2-Amino-3-iodopyridine

2-bromo-2- (ethylthio) -1- [3-methyl-6- (trifluoromethyl) -3H-imidazo [4,5-b] pyridine- 2 obtained in Step 5 of Intermediate Synthesis Example 1 -yl] ethan-1-one and 19 ml of acetonitrile was added 1.39 g of 3-iodopyridin-2-amine at room temperature. The reaction mixture was stirred under heating reflux for 9 hours. After completion of the reaction, 50 ml of water was added to the reaction mixture, and the mixture was extracted with chloroform (100 ml). The obtained organic layer was dehydrated with anhydrous sodium sulfate and dried, and then the solvent was distilled off under reduced pressure to obtain 2.0 g of the objective compound as a brown solid.

The synthetic route of 104830-06-0 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; ??????????; Tsuji Keisuke; Kudo Takao; Maizuru Yukihiro; Noto Kenkichi; Dai ? Nishi ? Atsuko; Matsui Yo Jin; Kobayashi Masaki; Kon Naka Hotaka; (136 pag.)JP2018/70585; (2018); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem