The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 131747-55-2, name is 2-Fluoro-3-(hydroxymethyl)pyridine. This compound has unique chemical properties. The synthetic route is as follows. Application In Synthesis of 2-Fluoro-3-(hydroxymethyl)pyridine
To a solution of (2-fluoropyridin-3-yl)methanol (500 mg 3.93 mmol) in DCM (15 mL) at 0 C. was added phosphorus tribromide (2.13 g, 7.87 mmol). The reaction mixture was stirred at room temperature for 16 hours. Water (10 mL) was added and the mixture was extracted with ethyl acetate (30 mL*3). The combined organic layers were washed with brine (20 mL), dried over Na2SO4 and concentrated to give 5-((tert-butyldimethylsilyl)oxy)pentan-1-ol.
With the rapid development of chemical substances, we look forward to future research findings about 131747-55-2.
Reference:
Patent; H. Lundbeck A/S; Juhl, Karsten; Jessing, Mikkel; Langgard, Morten; Vital, Paulo Jorge Vieira; Kehler, Jan; Rasmussen, Lars Kyhn; Clementson, Carl Martin Sebastian; Marigo, Mauro; US2019/185489; (2019); A1;,
Pyridine – Wikipedia,
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