Extracurricular laboratory: Synthetic route of 3-Fluoropicolinonitrile

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,97509-75-6, its application will become more common.

Related Products of 97509-75-6, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 97509-75-6, name is 3-Fluoropicolinonitrile. A new synthetic method of this compound is introduced below.

The mixture of 3-fluoro-pyridine-2-carbonitrile (0.81 g,6.63 mmol) and Pd/C (0.20 g, 10percent wt) in 10 ml of MeOH and2.7 ml of concentrated HC1 was placed under H2 which wasprovided by a balloon and stirred at RT for 4 h, filteredthrough Celite.(R)., condensed, the residue was purified byflash column chromatography, 0.13 g of the titled compoundwas obtained as a light yellowish oil. MS(ES+): 127.1(M+H)+. Calc’d for C6H7PN2 – 126.13.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,97509-75-6, its application will become more common.

Reference:
Patent; AMGEN INC.; WO2006/12374; (2006); A1;,
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