Application of 65-22-5 ,Some common heterocyclic compound, 65-22-5, molecular formula is C8H10ClNO3, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
General procedure: The synthetic routes for ligands (H3L1-2*Cl) are presented in Scheme 2. Pyridoxal N(4)-substituted thiosemicarbazone hydrochloride has been prepared according to a modification of the procedure described in the literature [25]. Substituted thiosemicarbazide (2 mmol) was dissolved in 10 mL of ethanol with constant stirring, and was added to pyridoxal hydrochloride (2 mmol) dissolved in 10 mL of ethanol. The mixture was stirred at 80 C for 30 min. After the reaction mixture was cooled to room temperature, the yellow solid was isolated by filtration, washed with ethanol and dried in vacuo.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 65-22-5, 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Manikandan, Rajendran; Vijayan, Paranthaman; Anitha, Panneerselvam; Prakash, Govindan; Viswanathamurthi, Periasamy; Butcher, Ray Jay; Velmurugan, Krishnaswamy; Nandhakumar, Raju; Inorganica Chimica Acta; vol. 421; (2014); p. 80 – 90;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem