Electric Literature of 67443-38-3, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 67443-38-3, name is 5-Bromo-2-chloro-3-nitropyridine. This compound has unique chemical properties. The synthetic route is as follows.
5-bromo-2-chloro-3-nitropyridine (5.73 g, 24.15 mmol) was dissolved in dry THF (50 ml, 610 mmol) and TEA (10.10 ml, 72.4 mmol) under nitrogen, 2-(tetrahydro-2H-pyran-4-yl)ethanamine hydrochloride (5 g, 30.2 mmol) was added and the resulting suspension stirred at RT over the weekend. The reaction mixture was poured onto ice/water (100 ml), the resulting yellow precipitate filtered off, washed with ice cold water (25 ml), dried in vacuo to give (7.49 g, 92%) as a bright yellow solid; m/z 330/332 (M+H)+(ES+);
According to the analysis of related databases, 67443-38-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; CELLCENTRIC LTD; PEGG, Neil Anthony; TADDEI, David Michel Adrien; BROWN, Richard; (63 pag.)WO2016/170323; (2016); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem