Related Products of 7418-65-7 , The common heterocyclic compound, 7418-65-7, name is 4-Aminonicotinic acid, molecular formula is C6H6N2O2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
2-Methyl-4H-pyrido[4,3-d][1,3]oxazin-4-one (17): The suspension of 16 (1.0 g, 7.3 mmol) in 6 mL of acetic anhydride was stirred under reflux for 2 h. The resulting orange solution was cooled to RT. The reaction mixture was concentrated in vacuo and the product was recrystallized from EtOAc to afford 0.65 g of compound 17 (56% yield).
The synthetic route of 7418-65-7 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; HYDRA BIOSCIENCES, INC.; Chong, Jayhong A.; Fanger, Christopher; Larsen, Glenn R.; Moran, Magdalene M.; Ng, Howard; Ripka, Amy; Underwood, Dennis John; Weigele, Manfred; Zhen, Xiaoguang; (83 pag.)US9486455; (2016); B2;,
Pyridine – Wikipedia,
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