Reference of 944401-56-3, Adding some certain compound to certain chemical reactions, such as: 944401-56-3, name is 5-Bromo-4-(trifluoromethyl)pyridin-2-amine,molecular formula is C6H4BrF3N2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 944401-56-3.
Method 4: N’-(5-bromo-4-(trifluoromethyl)pyridin-2-yl)-N,N-dimethylformimidamide (I9) (0161) (0162) 2-amino-6-(trifluoromethyl)pyridine (25.0 g, 156 mmol, 1.0 eq.) in dimethyl acetal (25.1 mL, 188 mmol, 1.2 eq.) was added and the mixture was heated at 70 C for 6 hours. The solvent was oratory evaporated under reduced pressure and the residue was recrystallized from hexane to yield the desired 29 product I9 as an off-white solid (65% yield). 1H NMR (400 MHz, CDCl3): delta 8.46 (s, 1 H), 8.38 (s, 1 H), 7.18 (s, 1 H), 3.11 (s, 3 H), 3.08 (s, 3 H); 19F{1H} NMR (376 MHz, CDCl3): delta – 65.0 (s, 3 F).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 944401-56-3, 5-Bromo-4-(trifluoromethyl)pyridin-2-amine, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Universitaet Basel; Bohnacker, Thomas; Rageot, Denise; Sele, Alexander Markus; Beaufils, Florent; Wymann, Matthias; (51 pag.)EP3231799; (2017); A1;,
Pyridine – Wikipedia,
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