Let¡¯s face it, organic chemistry can seem difficult to learn, Computed Properties of C9H13N3, Especially from a beginner¡¯s point of view. Like 34803-66-2, Name is 1-(2-Pyridyl)piperazine, molecular formula is pyridine-derivatives, belongs to pyridine-derivatives compound. In a document, author is Xie, Huan-Ping, introducing its new discovery.
Copper-Catalyzed Alkynylation/Cyclization/Isomerization Cascade for Synthesis of 1,2-Dihydrobenzofuro[3,2-b]pyridines and Benzofuro[3,2-b]pyridines
An efficient copper-catalyzed cascade alkynylation/cyclization/isomerization reaction of aurone-derived azadienes with terminal alkynes has been developed, giving a series of 1,2-dihydrobenzofuro[3,2-b]pyridines with excellent yields. The obtained 1,2-dihydrobenzofuro[3,2-b]pyridines can be conveniently transformed into the corresponding benzofuro[3,2-b]pyridines under basic conditions. Additionally, benzofuro[3,2-b]pyridines can also be prepared from azadienes and terminal alkynes in a one-pot reaction. The synthetic utility was demonstrated by the synthesis of three bioactive molecules with potent topoisomerase inhibition in high yields. This strategy provides a facile approach to 1,2-dihydrobenzofuro[3,2-b]pyridines and benzofuro[3,2-b]pyridines.
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Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem