Related Products of 4930-98-7, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 4930-98-7, Name is 2-Hydrazinylpyridine, SMILES is NNC1=NC=CC=C1, belongs to pyridine-derivatives compound. In a article, author is Kuthyala, Sharanya, introduce new discover of the category.
Towards the Synthesis of Imidazopyridine Derivatives: Characterization, Single Crystal XRD, Hirshfeld Analysis, and Biological Evaluation
This study explores the synthesis of different imidazopyridine derivatives, their characterization, single crystal x-ray diffraction, molecular Hirshfeld surface analysis along with their anticancer and other supportive biological evaluations. X-ray crystallography study resolved the crystal structure of 2,7-dimethyl-N-(1,3-dioxoisoindolin-2-yl)H-imidazo[1,2-a]pyridine-3-carboxamide (2 a) as monoclinic crystal system (space group P2(1)/n). Graphical tool, Hirshfeld surface analysis quantified the major contribution of H…H, O…H, and C…H interactions towards the HS. Among the synthesized compounds, 2-(4-(4-fluorophenyl)-5-(2,8-dimethylH-imidazo[1,2-a]pyridin-3-yl)-4H-1,2,4-triazol-3-ylthio)-N-(4-fluorophenyl)acetamide (5 a) exhibited the highest cytotoxicity against lung adenocarcinoma with IC50 value of 43.04 mu M. Selective action of 5 a was assured by cell death analysis using AO-EB assay. In addition, the study was also supported by molecular docking studies. Together the study revealed, the compound 5 a, to be a likely candidate for further exploratory study in cancer treatment.
Related Products of 4930-98-7, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 4930-98-7 is helpful to your research.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem