Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Al-Hazmi, Gamil A. A., once mentioned the application of 220000-87-3, Name is 4-Chloro-N-methylpicolinamide, molecular formula is C7H7ClN2O, molecular weight is 170.6, MDL number is MFCD02185921, category is pyridine-derivatives. Now introduce a scientific discovery about this category, HPLC of Formula: C7H7ClN2O.
Green synthesis approach for Fe (III), Cu (II), Zn (II) and Ni (II)-Schiff base complexes, spectral, conformational, MOE-docking and biological studies
Green synthesis of Fe (III), Cu (II), Zn (II) and Ni (II)-Schiff’s-base complexes from 2-oxo-N-(pyridine-2-yl)-2-(2-(1-(pyridin-2-yl)ethylidene)hydrazinyl)acetamide(H2L)ligand. All new complexes were characterized via several spectroscopic and analytical techniques, to establish their molecular and structural formulae. All complexes appeared have 1:1 molar ratio (M:L). The ligand contributed as a neutral poly-dentate towards the metal ions. Moreover, material-studio program was used to predict the most fitted atomic-skeletons for investigated compounds by applying DFT method. MOE docking module (vs. 2015) was used to examine the degree of inhibition for new compounds versus three infected-cell proteins (1bqb, 2gt1 and 4esw). Also, antimicrobial and colorimetric assess for compounds that bind DNA were performed
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Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem