Flouzat, Christine; Guillaumet, Gerald published an article on January 31 ,1990. The article was titled ãA new convenient synthesis of 2-aryl- and 2-heteroaryloxazolo[5,4-b]pyridinesã? and you may find the article in Synthesis.COA of Formula: C12H8ClN3O3 The information in the text is summarized as follows:
Aminochloropyridines I (R = H, Cl) were treated with R1COCl (R1 = Ph, 2-FC6H4, 4-ClC6H4, 2-ClC6H4, 4-MeOC6H4, 2-O2NC6H4, 4-MeC6H4, 4-NCC6H4, 2-furyl, 2-thienyl) to give 95-98% amides II. Heating II in the presence of trimethylsilyl polyphosphate ester with or without a solvent (1,2-dichlorobenzene) gave 75-98% oxazolopyridines III. In the experiment, the researchers used many compounds, for example, N-(2-Chloropyridin-3-yl)-2-nitrobenzamide(cas: 1028-86-0COA of Formula: C12H8ClN3O3)
N-(2-Chloropyridin-3-yl)-2-nitrobenzamide(cas: 1028-86-0) belongs to anime. Reaction with nitrous acid (HNO2), which functions as an acylating agent that is a source of the nitrosyl group (―NO), converts aliphatic primary amines to nitrogen and mixtures of alkenes and alcohols corresponding to the alkyl group in a complex process. This reaction has been used for analytical determination of primary amino groups in a procedure known as the Van Slyke method.COA of Formula: C12H8ClN3O3