Hydroarylation of Arenes via Reductive Radical-Polar Crossover was written by Flynn, Autumn R.;McDaniel, Kelly A.;Hughes, Meredith E.;Vogt, David B.;Jui, Nathan T.. And the article was included in Journal of the American Chemical Society in 2020.Name: tert-Butyl (3-bromopyridin-4-yl)carbamate This article mentions the following:
A photocatalytic system for the dearomative hydroarylation of benzene derivatives has been developed. Using a combination of an organic photoredox catalyst and an amine reductant, this process operates through a reductive radical-polar crossover mechanism where aryl halide reduction triggers a regioselective radical cyclization event, followed by anion formation and quenching to produce a range of complex spirocyclic cyclohexadienes. This light-driven protocol functions at room temperature in a green solvent system (aqueous MeCN) without the need for precious metal-based catalysts or reagents or the generation of stoichiometric metal byproducts. In the experiment, the researchers used many compounds, for example, tert-Butyl (3-bromopyridin-4-yl)carbamate (cas: 257937-08-9Name: tert-Butyl (3-bromopyridin-4-yl)carbamate).
tert-Butyl (3-bromopyridin-4-yl)carbamate (cas: 257937-08-9) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 锜?bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 锜?bonds. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Name: tert-Butyl (3-bromopyridin-4-yl)carbamate