Name: Methyl 5-bromopicolinateIn 2014 ,《An environmentally-friendly one-pot synthesis of 4-sulfonyl benzoic acids》 was published in Tetrahedron Letters. The article was written by Frieman, Bryan A.. The article contains the following contents:
This Letter reported an environmentally-friendly one-pot SNAr reaction of thiols to 4-halobenzoic acid Me esters to provide 4-substituted sulfone benzoic acids and picolinic acids after bleach-mediated oxidative workup. These acid intermediates were synthesized on gram scale, are perfect partners for library synthesis, and have good phys. chem. properties useful for drug discovery. In the experimental materials used by the author, we found Methyl 5-bromopicolinate(cas: 29682-15-3Name: Methyl 5-bromopicolinate)
Methyl 5-bromopicolinate(cas: 29682-15-3) belongs to pyridine. Pyridines, quinolines, and isoquinolines have found a function in almost all aspects of organic chemistry. Pyridine has found use as a solvent, base, ligand, functional group, and molecular scaffold. As structural elements, these moieties are potent electron-deficient groups, metal-directing functionalities, fluorophores, and medicinally important pharmacophores. Name: Methyl 5-bromopicolinate