In 2017,Fu, Haiyan; Shen, Peng-Xiang; He, Jian; Zhang, Fanglin; Li, Suhua; Wang, Peng; Liu, Tao; Yu, Jin-Quan published 《Ligand-Enabled Alkynylation of C(sp3)-H Bonds with Palladium(II) Catalysts》.Angewandte Chemie, International Edition published the findings.HPLC of Formula: 128071-75-0 The information in the text is summarized as follows:
The palladium(II)-catalyzed β- and γ-alkynylation of amide C(sp3)-H bonds is enabled by pyridine-based ligands. This alkynylation reaction is compatible with substrates containing α-tertiary or α-quaternary carbon centers. The β-methylene C(sp3)-H bonds of various carbocyclic rings were also successfully alkynylated. The experimental process involved the reaction of 2-Bromonicotinaldehyde(cas: 128071-75-0HPLC of Formula: 128071-75-0)
2-Bromonicotinaldehyde(cas: 128071-75-0) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.HPLC of Formula: 128071-75-0