Determination of the binding situation of pyridine in xylan sulfates by means of detailed NMR studies was written by Gabriel, Lars;Guenther, Wolfgang;Pielenz, Friederike;Heinze, Thomas. And the article was included in Macromolecular Chemistry and Physics in 2020.SDS of cas: 628-13-7 This article mentions the following:
Xylan sulfate is an important drug to treat interstitial cystitis. Production of the drug by sulfation of the polysaccharide with a sulfating agent like chlorosulfuric acid and pyridine-SO3 complex in pyridine may lead to products containing pyridine-based impurities. Xylan sulfate containing nitrogen is investigated by different NMR measurements in order to clarify the binding situation of pyridine. The detailed NMR studies allow the conclusion that the pyridine-based impurities are covalently bonded to the reducing end group. Furthermore, the NMR spectroscopic investigation indicates that the side reactions occur at shorter polymer chains only. In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7SDS of cas: 628-13-7).
Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.SDS of cas: 628-13-7