Dephosphorylation of pyridoxal 5′-phosphate-derived Schiff bases in the presence of bovine alkaline phosphatase was written by Gamov, George;Murekhina, Anastasia;Aleksandriiskii, Viktor. And the article was included in International Journal of Chemical Kinetics in 2022.Application In Synthesis of (4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate The following contents are mentioned in the article:
The present paper reports on the study of the dephosphorylation of pyridoxal 5′-phosphate and four derived hydrazones (containing the residues of pyrazine, 2-furan, 2-thiophene, 3-pyridine carboxylic acids) induced by bovine alk. phosphatase from intestinal mucosa at 298.2 K and pH 10 (0.05 m Tris-HCl buffer). We observed and discussed characteristic changes in the UV-vis and fluorescent spectra of substrates. Michaelis-Menten parameters of the enzymic dephosphorylation are calculated The stability of alk. phosphatase in the presence of hydrazones is confirmed. The dephosphorylation of the Zn(II) complex with pyridoxal 5′-phosphate-derived hydrazone is analyzed. This study involved multiple reactions and reactants, such as (4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate (cas: 54-47-7Application In Synthesis of (4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate).
(4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate (cas: 54-47-7) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Application In Synthesis of (4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate