Pd-Catalyzed Directed Thiocyanation Reaction by C-H Bond Activation was written by Gao, Melissa;Chen, Mu-Yi;Pannecoucke, Xavier;Jubault, Philippe;Besset, Tatiana. And the article was included in Chemistry – A European Journal in 2020.Name: 2-(m-Tolyl)pyridine This article mentions the following:
The Pd-catalyzed directed thiocyanation reaction of arenes and heteroarenes by C-H bond activation was achieved. In the presence of an electrophilic SCN source, this original methodol. offered an efficient tool to access a panel of functionalized thiocyanated compounds I (R = H, 2-F, 4-OMe, etc.; DG = pyridin-2-yl, pyrimidin-2-yl, pyrazol-1-yl) (21 examples, up to 78% yield). Post-functionalization reactions further demonstrated the synthetic utility of the approach by converting the SCN-containing mols. into value-added scaffolds. In the experiment, the researchers used many compounds, for example, 2-(m-Tolyl)pyridine (cas: 4373-61-9Name: 2-(m-Tolyl)pyridine).
2-(m-Tolyl)pyridine (cas: 4373-61-9) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Name: 2-(m-Tolyl)pyridine