Chemoselective and ligand-free synthesis of diaryl ethers in aqueous medium using recyclable alumina-supported nickel nanoparticles was written by Ghatak, Avishek;Khan, Sagar;Roy, Rimi;Bhar, Sanjay. And the article was included in Tetrahedron Letters in 2014.Application of 4783-68-0 This article mentions the following:
An economical and eco-compatible ligand-free protocol for the synthesis of diaryl ethers R1OR2 (R1 = Ph, 2-pyridyl, 3-pyridyl, etc.; R2 = Ph, 2-MeC6H4, 4-ClC6H4, 2-naphthyl, etc.) from the corresponding aryl halides R1X (X = Cl, Br, I) and phenols R2OH has been developed using easily accessible alumina-supported nickel nanoparticles as a stable recyclable heterogeneous catalyst in aqueous medium along with a surfactant (SDS) and a mild base (K2CO3). Various sensitive functional groups like allyl, alkoxycarbonyl, formyl, oxo, chloro, bromo, amine and nitro were tolerated in this method. Excellent chemoselectivity was demonstrated through competition experiments In the experiment, the researchers used many compounds, for example, 2-Phenoxypyridine (cas: 4783-68-0Application of 4783-68-0).
2-Phenoxypyridine (cas: 4783-68-0) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Application of 4783-68-0