Ghosh, Kajari; Molla, Rostam Ali; Iqubal, Asif Md.; Islam, S. M. published the artcile< A mesoporous organosilica grafted Pd catalyst (MOG-Pd) for efficient base free and phosphine free synthesis of tertiary butyl esters via tertiary-butoxycarbonylation of boronic acid derivatives without using carbon monoxide>, Category: pyridine-derivatives, the main research area is silica palladium preparation alkoxycarbonylation catalyst green chem.
A mesoporous organosilica grafted palladium(II) catalyst was synthesized and characterized using various spectroscopic techniques. Its catalytic activity was evaluated for the synthesis of tert-Bu esters by tert-butoxycarbonylation of boronic acid derivatives The tert-Bu esters were obtained directly from boronic acid pinacol esters and di-tert-Bu dicarbonate. The reaction was optimized by varying the bases, temperatures and solvents (green chem. method). The catalyst was very stable and could be facilely recovered and reused six times with no significant decrease in its activity and selectivity. The synthesis of the target compounds was achieved using mesoporous-silica-supported furanmethanimine-palladium diacetate (i.e., Schiff-base-imine-palladium complex) as a catalyst. The starting materials included dicarbonic acid 1,3-bis(1,1-dimethylethyl) ester and 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine derivatives, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinecarbonitrile (nitrile), 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinecarboxylic acid ester (pyridine), 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline, 4,4,5,5-tetramethyl-2-(2-methylphenyl)-1,3,2-dioxaborolane derivatives, 4,4,5,5-tetramethyl-2-(2-thienyl)-1,3,2-dioxaborolane (thiophene derivative). The title compounds thus formed included 2-pyridinecarboxylic acid 1,1-dimethylethyl ester, 3-pyridinecarboxylic acid 1,1-dimethylethyl ester, 4-pyridinecarboxylic acid 1,1-dimethylethyl ester, 3,5-pyridinedicarboxylic acid 3-(1,1-dimethylethyl) 5-Et ester, 4-quinolinecarboxylic acid 1,1-dimethylethyl ester, benzoic acid 1,1-dimethylethyl ester derivatives
Green Chemistry published new progress about Alkoxycarbonylation. 832735-54-3 belongs to class pyridine-derivatives, and the molecular formula is C18H22BNO3, Category: pyridine-derivatives.