Gomez Fernandez, Mario Andres published the artcileStudies on The Application of The Paterno-Buechi Reaction to The Synthesis of Novel Fluorinated Scaffolds, Quality Control of 91-02-1, the publication is Chemistry – A European Journal (2021), 27(63), 15722-15729, database is CAplus and MEDLINE.
In the context of new scaffolds obtained by photochem. reactions, Paterno-Buechi reactions between heteroaromatic, trifluoromethylphenyl ketone and electron rich alkenes to give oxetanes are described. A comprehensive study has been carried out on the reaction of aromatic ketones with fluorinated alkenes. Depending on the substitution pattern at the oxetane ring, a metathesis reaction is described as a minor side process to give mono-fluorinated alkenes. Overall, this last reaction corresponds to a photo-Wittig reaction and yields amide isosteres. In order to explain the uncommon regioselectivity of the Paterno-Buechi reaction with these alkenes, electrostatic-potential-derived charges (ESP) have been determined In a second computational study, the relative stabilities of the typical 1,4-diradical intermediates of the Paterno-Buechi reaction have been determined The results explain the regioselectivity. Further transformations of the oxetanes or previous functionalization of the fluoroalkenes open perspectives for oxetanes as core structures for biol. active compounds
Chemistry – A European Journal published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C12H9NO, Quality Control of 91-02-1.
Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem