Ruthenium-catalyzed ortho-selective CAr-H amination of heteroaryl arenes with di-tert-butyldiaziridinone was written by Gou, Xue-Ya;Li, Yuke;Wang, Xin-Gang;Liu, Hong-Chao;Zhang, Bo-Sheng;Zhao, Jia-Hui;Zhou, Zhao-Zhao;Liang, Yong-Min. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2019.HPLC of Formula: 4373-61-9 This article mentions the following:
Application of an oxidative amination reagent (di-tert-butyldiaziridinone) to the Ru3(CO)12-catalyzed ortho-selective CAr-H amination reaction was described. This strategy showed good functional group compatibility with various phenyl-substituted N-heterocycles, including biol. active substrates, thus providing synthetic potential for this methodol. Mechanistic studies showed that the reaction process involves an octahedral ruthenium species, and the carbon monoxide ligand plays a crucial role in the C-H activation. In the experiment, the researchers used many compounds, for example, 2-(m-Tolyl)pyridine (cas: 4373-61-9HPLC of Formula: 4373-61-9).
2-(m-Tolyl)pyridine (cas: 4373-61-9) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. HPLC of Formula: 4373-61-9