Gu, Yiting; Shen, Yangyang; Zarate, Cayetana; Martin, Ruben published the artcile< A Mild and Direct Site-Selective sp2 C-H Silylation of (Poly)Azines>, Product Details of C6H4F3N, the main research area is silylation pyridine pyrimidine pyrazine quinoline silyl dioxaborolane reagent; base promoted silylation azine borylsilane regioselective orthogonal process.
A base-mediated protocol that allows for the site-selective sp2 C-H silylation of pyridines, pyrazines, pyridazines, pyrimidines and quinolines by Et3SiBpin is described. The substitution typically proceeds in 4- or 2-position of the pyridine ring. This method is distinguished by its mild conditions, simplicity and excellent site-selective modulation for a diverse set of azines, even in the context of late-stage functionalization, while exhibiting orthogonal reactivity with classical silylation reactions.
Journal of the American Chemical Society published new progress about Boronic acids, esters Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (borylsilanes). 3796-23-4 belongs to class pyridine-derivatives, and the molecular formula is C6H4F3N, Product Details of C6H4F3N.