Gudmundsson, Kristjan S.; Hinkley, Jack M.; Brieger, Michael S.; Drach, John C.; Townsend, Leroy B. published the artcile< An improved large-scale synthesis of 2-amino-4-chloropyridine and its use for the convenient preparation of various polychlorinated 2-aminopyridines>, Category: pyridine-derivatives, the main research area is aminochloropyridine preparation chlorination; polychlorinated aminopyridine preparation; pyridine amino polychlorinated preparation.
An efficient large scale synthesis of 2-amino-4-chloropyridine (I) has been achieved through a modification of existing literature procedures. I was used to prepare the previously unreported 2-amino-4,5-dichloropyridine. The known 2-amino-3,4-dichloropyridine and 2-amino-3,4,5-trichloropyridine were prepared from I by new routes and in higher yields than previously reported.
Synthetic Communications published new progress about 188577-68-6. 188577-68-6 belongs to class pyridine-derivatives, and the molecular formula is C5H4Cl2N2, Category: pyridine-derivatives.