Iodine-promoted controlled and selective oxidation of (aryl)(heteroaryl)methanes was written by Guha, Somraj;Kazi, Imran;Sathish, Dhamodharan;Sekar, Govindasamy. And the article was included in Journal of Organic Chemistry in 2022.Name: Phenyl(pyridin-2-yl)methanone This article mentions the following:
Herein, an iodine-catalyzed controlled oxidation of (aryl)(heteroaryl)methanes to (aryl)(heteroaryl)methanols ArCH(O)Ar1 [Ar = Ph, 2-MeC6H4, 4-ClC6H4, etc.; Ar1 = pyridin-2-yl, benzothiazol-2-yl] was disclosed under metal-free reaction conditions. A catalytic system comprised of iodine/silyl chloride with HI as an additive in the presence of DMSO selectively oxidize the C(sp3)-H bonds without being over oxidized to corresponding ketones. Therapeutically important aryl heteroaryl methanol derivatives were obtained in good yields. The preliminary mechanistic investigation proved that the primary source of oxygen was DMSO. In the experiment, the researchers used many compounds, for example, Phenyl(pyridin-2-yl)methanone (cas: 91-02-1Name: Phenyl(pyridin-2-yl)methanone).
Phenyl(pyridin-2-yl)methanone (cas: 91-02-1) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Name: Phenyl(pyridin-2-yl)methanone