Guha, Somraj’s team published research in Journal of Organic Chemistry in 87 | CAS: 91-02-1

Journal of Organic Chemistry published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C12H9NO, Category: pyridine-derivatives.

Guha, Somraj published the artcileIodine-promoted controlled and selective oxidation of (aryl)(heteroaryl)methanes, Category: pyridine-derivatives, the publication is Journal of Organic Chemistry (2022), 87(8), 5424-5429, database is CAplus and MEDLINE.

Herein, an iodine-catalyzed controlled oxidation of (aryl)(heteroaryl)methanes to (aryl)(heteroaryl)methanols ArCH(O)Ar1 [Ar = Ph, 2-MeC6H4, 4-ClC6H4, etc.; Ar1 = pyridin-2-yl, benzothiazol-2-yl] was disclosed under metal-free reaction conditions. A catalytic system comprised of iodine/silyl chloride with HI as an additive in the presence of DMSO selectively oxidize the C(sp3)-H bonds without being over oxidized to corresponding ketones. Therapeutically important aryl heteroaryl methanol derivatives were obtained in good yields. The preliminary mechanistic investigation proved that the primary source of oxygen was DMSO.

Journal of Organic Chemistry published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C12H9NO, Category: pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem