Safety of 4-CyanopyridineIn 2020 ,《Niacin as a Potent Organocatalyst towards the Synthesis of Quinazolines Using Nitriles as C-N Source》 appeared in European Journal of Organic Chemistry. The author of the article were Gujjarappa, Raghuram; Vodnala, Nagaraju; Reddy, Velma Ganga; Malakar, Chandi C.. The article conveys some information:
An efficient and cost-effective Vitamin-B3-catalyzed protocol towards the synthesis of diversely substituted quinazolines is illustrated using 2-aminobenzylamines and nitriles as substrates. An organocatalytic transformation has been investigated where nitrile plays a role of C-N bond donor. The developed approach is applicable on a wide range of 2-aminobenzylamines and nitriles for the synthesis of substituted quinazolines in high yields with a broad functional group tolerance.4-Cyanopyridine(cas: 100-48-1Safety of 4-Cyanopyridine) was used in this study.
4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine and pyridine-derived structures are privileged pharmacophores in medicinal chemistry and an essential functionality for organic chemists. As the prototypical π-deficient heterocycle, pyridine illustrates distinctive chemistry as both substrate and reagent. Safety of 4-Cyanopyridine