Gujral, Gurjeet; Bhasin, K. K.; Gulati, Shivani published their research in Indian Journal of Heterocyclic Chemistry in 2021. The article was titled 《A new synthetic methodology for the preparation 2-Pyridyl anisyl/benzyl selenides: X-Ray Crystal Structure of 2-(4-Methyl pyridyl)tolyl selenide》.Synthetic Route of C5H3Br2N The article contains the following contents:
An effective methodol. for the synthesis of these selenides had been developed by reacting dianisyl/dibenzyl diselenide with substituted/unsubstituted 2-pyridyl halides in the presence of activated magnesium metal, Cu2O, and bipyridyl in DMF at 110°C for 18-20 h. The newly synthesized 2-pyridyl anisyl/benzyl selenides were either viscous liquids or crystalline solids that were stable at room temperature for several months without decomposition These were fully characterized by various spectroscopic techniques, namely, NMR (1H, 13C, and 77Se), IR, and mass spectroscopy. Single-crystal X-ray diffraction study of 2-(4-methylpyridyl) tolyl selenide was carried out to know the structural details of the mol. and well-defined diffraction quality crystals of 2-(4-Me pyridyl)tolyl selenide were obtained by slow evaporation of saturated solution of the compound in hexane-dichloromethane solvent mixture (4:1, volume/volume).2,5-Dibromopyridine(cas: 624-28-2Synthetic Route of C5H3Br2N) was used in this study.
2,5-Dibromopyridine(cas: 624-28-2) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Synthetic Route of C5H3Br2N